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Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma
The AKT and NF-κB pathways are central regulators of cellular signaling events at the basis of tumor development and progression. Both pathways are often up-regulated in different tumor types including melanoma. We recently reported the identification of compound 1 (BI-69A11) as inhibitor of the AKT...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966491/ https://ncbi.nlm.nih.gov/pubmed/23790042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12177 |
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