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Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

Neutralizing antibodies against influenza viruses have traditionally been thought to provide protection exclusively through their variable region; the contributions of mechanisms conferred by the Fc domain remain controversial. We investigated the in vivo contributions of Fc interactions with their...

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Detalhes bibliográficos
Main Authors: DiLillo, David J, Tan, Gene S, Palese, Peter, Ravetch, Jeffrey V
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966466/
https://ncbi.nlm.nih.gov/pubmed/24412922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3443
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