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TACE-dependent TGF-alpha shedding drives triple-negative breast cancer cell invasion

The Epidermal Growth Factor Receptor is frequently expressed in triple-negative breast cancer and is a marker of poor prognosis in this patient population. Because activating mutations in this kinase are very rare events in breast cancer, we screened breast tumor gene expression profiles to examine...

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Detalhes bibliográficos
Main Authors: Giricz, Orsi, Calvo, Veronica, Peterson, Esther A., Abouzeid, Christiane M., Kenny, Paraic A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966141/
https://ncbi.nlm.nih.gov/pubmed/23729230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28295
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