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ATPγS Competes with ATP for Binding at Domain 1 but not Domain 2 during ClpA Catalyzed Polypeptide Translocation

ClpAP is an ATP-dependent protease that assembles through the association of hexameric rings of ClpA with the cylindrically-shaped protease ClpP. ClpA contains two nucleotide binding domains, termed Domain 1 (D1) or 2 (D2). We have proposed that D1 or D2 limit the rate of ClpA catalyzed polypeptide...

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Detalhes bibliográficos
Main Authors: Miller, Justin M., Lucius, Aaron L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966025/
https://ncbi.nlm.nih.gov/pubmed/24362308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.11.002
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