Role of the Lipoxygenase Pathway in RSV-induced Alternatively Activated Macrophages Leading to Resolution of Lung Pathology

Resolution of severe RSV-induced bronchiolitis is mediated by alternatively activated macrophages (AA-Mϕ) that counteract cyclooxygenase (COX)-2-induced lung pathology. Herein, we report that RSV infection of 5-lipoxygenase (LO)(−/−) and 15-LO(−/−) macrophages or mice failed to elicit AA-Mϕ differen...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shirey, Kari Ann, Lai, Wendy, Pletneva, Lioubov M., Karp, Christopher L., Divanovic, Senad, Blanco, Jorge C. G., Vogel, Stefanie N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965659/
https://ncbi.nlm.nih.gov/pubmed/24064666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.71
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares