Interleukin-6 Secretion by Astrocytes Is Dynamically Regulated by PI3K-mTOR-Calcium Signaling

After contusion spinal cord injury (SCI), astrocytes become reactive and form a glial scar. While this reduces spreading of the damage by containing the area of injury, it inhibits regeneration. One strategy to improve the recovery after SCI is therefore to reduce the inhibitory effect of the scar,...

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Autori principali: Codeluppi, Simone, Fernandez-Zafra, Teresa, Sandor, Katalin, Kjell, Jacob, Liu, Qingsong, Abrams, Mathew, Olson, Lars, Gray, Nathanael S., Svensson, Camilla I., Uhlén, Per
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965459/
https://ncbi.nlm.nih.gov/pubmed/24667246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092649
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