The Rheb–mTOR Pathway Is Upregulated in Reactive Astrocytes of the Injured Spinal Cord

Astrocytes in the CNS respond to tissue damage by becoming reactive. They migrate, undergo hypertrophy, and form a glial scar that inhibits axon regeneration. Therefore, limiting astrocytic responses represents a potential therapeutic strategy to improve functional recovery. It was recently shown th...

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Detalhes bibliográficos
Main Authors: Codeluppi, Simone, Svensson, Camilla I., Hefferan, Michael P., Valencia, Fatima, Silldorff, Morgan D., Oshiro, Masakatsu, Marsala, Martin, Pasquale, Elena B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682457/
https://ncbi.nlm.nih.gov/pubmed/19176818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4103-08.2009
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