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Interleukin-6 Secretion by Astrocytes Is Dynamically Regulated by PI3K-mTOR-Calcium Signaling

After contusion spinal cord injury (SCI), astrocytes become reactive and form a glial scar. While this reduces spreading of the damage by containing the area of injury, it inhibits regeneration. One strategy to improve the recovery after SCI is therefore to reduce the inhibitory effect of the scar,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Codeluppi, Simone, Fernandez-Zafra, Teresa, Sandor, Katalin, Kjell, Jacob, Liu, Qingsong, Abrams, Mathew, Olson, Lars, Gray, Nathanael S., Svensson, Camilla I., Uhlén, Per
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965459/
https://ncbi.nlm.nih.gov/pubmed/24667246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092649
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