mTOR Mediated Anti-Cancer Drug Discovery

Podobne zapisy

• Development of ATP-competitive mTOR Inhibitors
  od: Liu, Qingsong, i wsp.
  Wydane: (2012)
• Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability
  od: Liu, Qingsong, i wsp.
  Wydane: (2011)
• Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective and orally available mTOR inhibitor for treatment of cancer
  od: Liu, Qingsong, i wsp.
  Wydane: (2011)
• DEPTOR is an mTOR Inhibitor Whose Frequent Overexpression in Multiple Myeloma Cells Promotes their Survival
  od: Peterson, Timothy R., i wsp.
  Wydane: (2009)
• Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective Mammalian Target of Rapamycin (mTOR) inhibitor for the treatment of cancer
  od: Liu, Qingsong, i wsp.
  Wydane: (2010)