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mTOR Mediated Anti-Cancer Drug Discovery

The mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase and the founding member of a signaling pathway that regulates many fundamental features of cell growth and division. In cells, mTOR acts as the catalytic subunit of two functionally distinct complexes, ca...

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Détails bibliographiques
Auteurs principaux: Liu, Qingsong, Thoreen, Carson, Wang, Jinhua, Sabatini, David, Gray, Nathanael S.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901551/
https://ncbi.nlm.nih.gov/pubmed/20622997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddstr.2009.12.001
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