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mTOR Mediated Anti-Cancer Drug Discovery
The mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase and the founding member of a signaling pathway that regulates many fundamental features of cell growth and division. In cells, mTOR acts as the catalytic subunit of two functionally distinct complexes, ca...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901551/ https://ncbi.nlm.nih.gov/pubmed/20622997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddstr.2009.12.001 |
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