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Design of Optimally Constructed Metabolic Networks of Minimal Functionality

BACKGROUND: Metabolic engineering aims to design microorganisms that will generate a product of interest at high yield. Thus, a variety of in silico modeling strategies has been applied successfully, including the concepts of elementary flux modes (EFMs) and constrained minimal cut sets (cMCSs). The...

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Detalhes bibliográficos
Main Authors: Ruckerbauer, David E., Jungreuthmayer, Christian, Zanghellini, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965433/
https://ncbi.nlm.nih.gov/pubmed/24667792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092583
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