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Designing minimal microbial strains of desired functionality using a genetic algorithm
BACKGROUND: The rational, in silico prediction of gene-knockouts to turn organisms into efficient cell factories is an essential and computationally challenging task in metabolic engineering. Elementary flux mode analysis in combination with constraint minimal cut sets is a particularly powerful met...
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| 出版年: | Algorithms Mol Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687386/ https://ncbi.nlm.nih.gov/pubmed/26697103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-015-0060-6 |
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