Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease.

The same heterozygous T -> C transition at nt 8567 of the von Willebrand factor (vWF) transcript was found in two unrelated patients with type III) von Willebrand disease, with no other apparent abnormality. In one family, both alleles were normal in the parents and one sister; thus, the mutation or...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Schneppenheim, R, Brassard, J, Krey, S, Budde, U, Kunicki, T J, Holmberg, L, Ware, J, Ruggeri, Z M
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1996
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622978/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3581
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!