Self-assembled RNA interference microsponges for efficient siRNA delivery

The encapsulation and delivery of short interfering RNA (siRNA) has been realized using lipid nanoparticles(1,2), cationic complexes(3,4), inorganic nanoparticles(5–8), RNA nanoparticles(9,10) and dendrimers(11). Still, the instability of RNA and the relatively ineffectual encapsulation process of s...

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Bibliografiske detaljer
Main Authors: Lee, Jong Bum, Hong, Jinkee, Bonner, Daniel K., Poon, Zhiyong, Hammond, Paula T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965374/
https://ncbi.nlm.nih.gov/pubmed/22367004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3253
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