Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference

RNA interference requires efficient delivery of small double-stranded RNA molecules into the target cells and their subsequent incorporation into RNA-induced silencing complexes. Although current cationic lipids commonly used for DNA transfection have also been used for siRNA transfection, a clear n...

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Detalhes bibliográficos
Main Authors: Desigaux, Léa, Sainlos, Matthieu, Lambert, Olivier, Chevre, Raphael, Letrou-Bonneval, Emilie, Vigneron, Jean-Pierre, Lehn, Pierre, Lehn, Jean-Marie, Pitard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034216/
https://ncbi.nlm.nih.gov/pubmed/17923669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707431104
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