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Self-assembled RNA interference microsponges for efficient siRNA delivery

The encapsulation and delivery of short interfering RNA (siRNA) has been realized using lipid nanoparticles(1,2), cationic complexes(3,4), inorganic nanoparticles(5–8), RNA nanoparticles(9,10) and dendrimers(11). Still, the instability of RNA and the relatively ineffectual encapsulation process of s...

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Detalhes bibliográficos
Main Authors: Lee, Jong Bum, Hong, Jinkee, Bonner, Daniel K., Poon, Zhiyong, Hammond, Paula T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965374/
https://ncbi.nlm.nih.gov/pubmed/22367004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3253
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