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Duality of the murine CD8 compartment

CD8αβ plays crucial roles in the thymic selection, differentiation, and activation of some, but not all, CD8(+) T cells, whereas CD8αα does not. To investigate these roles, we produced mice that expressed transgene P14 T-cell receptor β (TCRβ) chain and CD8β or did not (WT and KO mice, respectively)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Genolet, Raphaël, Leignadier, Julie, Østerås, Magne, Farinelli, Laurent, Stevenson, Brian J., Luescher, Immanuel F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964049/
https://ncbi.nlm.nih.gov/pubmed/24594598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317847111
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