Highly diverse TCRα chain repertoire of pre-immune CD8(+) T cells reveals new insights in gene recombination

Although the T-cell receptor αδ (TCRαδ) locus harbours large libraries of variable (TRAV) and junctional (TRAJ) gene segments, according to previous studies the TCRα chain repertoire is of limited diversity due to restrictions imposed by sequential coordinate TRAV-TRAJ recombinations. By sequencing...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Genolet, Raphael, Stevenson, Brian J, Farinelli, Laurent, Østerås, Magne, Luescher, Immanuel F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321212/
https://ncbi.nlm.nih.gov/pubmed/22373576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.48
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller