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Convallatoxin, a Dual Inducer of Autophagy and Apoptosis, Inhibits Angiogenesis In Vitro and In Vivo

Autophagy and apoptosis are important processes that control cellular homeostasis and have been highlighted as promising targets for novel cancer therapies. Here, we identified convallatoxin (CNT), isolated from Antiaris toxicaria, as a dual inducer of autophagy and apoptosis. CNT exerts cytotoxic e...

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Detalhes bibliográficos
Main Authors: Yang, Seung Ya, Kim, Nam Hee, Cho, Yoon Sun, Lee, Hukeun, Kwon, Ho Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963847/
https://ncbi.nlm.nih.gov/pubmed/24663328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091094
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