Betulinic Acid Inhibits Growth Factor‐induced in vitro Angiogenesis via the Modulation of Mitochondrial Function in Endothelial Cells

Betulinic acid (BetA), a pentacyclic triterpene, is a selective apoptosis‐inducing agent that works directly in mitochondria. Recent study has revealed that BetA inhibits in vitro enzymatic activity of aminopeptidase N (APN, EC 3.4.11.2), which is known to play an important role in angiogenesis, but...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kwon, Ho Jeong, Shim, Joong Sup, Kim, Jin Hee, Cho, Hyun Young, Yum, Young Na, Kim, Seung Hee, Yu, Jaehoon
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927016/
https://ncbi.nlm.nih.gov/pubmed/11985792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01273.x
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