The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis

R-(-)-β-O-methylsynephrine (OMe-Syn) is a naturally occurring small molecule that was identified in a previous screen as an inhibitor of angiogenesis. In this study, we conducted two animal model experiments to investigate the in vivo antiangiogenic activity of OMe-Syn. OMe-Syn significantly inhibit...

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Publicat a:Int J Biol Sci
Autors principals: Kim, Nam Hee, Pham, Ngoc Bich, Quinn, Ronald J., Shim, Joong Sup, Cho, Hee, Cho, Sung Min, Park, Sung Wook, Kim, Jeong Hun, Seok, Seung Hyeok, Oh, Jong-Won, Kwon, Ho Jeong
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515819/
https://ncbi.nlm.nih.gov/pubmed/26221075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10603
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