Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis

Tumor cells have high-energetic and anabolic needs and are known to adapt their metabolism to be able to survive and keep proliferating under conditions of nutrient stress. We show that PKCζ deficiency promotes the plasticity necessary for cancer cells to reprogram their metabolism to utilize glutam...

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Autors principals: Ma, Li, Tao, Yongzhen, Duran, Angeles, Llado, Victoria, Galvez, Anita, Barger, Jennifer F., Castilla, Elias A., Chen, Jing, Yajima, Tomoko, Porollo, Aleksey, Medvedovic, Mario, Brill, Laurence M., Plas, David R., Riedl, Stefan J., Leitges, Michael, Diaz-Meco, Maria T., Richardson, Adam D., Moscat, Jorge
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963830/
https://ncbi.nlm.nih.gov/pubmed/23374352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.028
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