Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis

Tumor cells have high-energetic and anabolic needs and are known to adapt their metabolism to be able to survive and keep proliferating under conditions of nutrient stress. We show that PKCζ deficiency promotes the plasticity necessary for cancer cells to reprogram their metabolism to utilize glutam...

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Main Authors: Ma, Li, Tao, Yongzhen, Duran, Angeles, Llado, Victoria, Galvez, Anita, Barger, Jennifer F., Castilla, Elias A., Chen, Jing, Yajima, Tomoko, Porollo, Aleksey, Medvedovic, Mario, Brill, Laurence M., Plas, David R., Riedl, Stefan J., Leitges, Michael, Diaz-Meco, Maria T., Richardson, Adam D., Moscat, Jorge
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963830/
https://ncbi.nlm.nih.gov/pubmed/23374352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.028
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