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Interferons limit inflammatory responses by induction of tristetraprolin

Interferons (IFNs) are cytokines with pronounced proinflammatory properties. Here we provide evidence that IFNs play a key role also in decline of inflammation by inducing expression of tristetraprolin (TTP). TTP is an RNA-binding protein that destabilizes several AU-rich element-containing mRNAs in...

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Detalhes bibliográficos
Main Authors: Sauer, Ines, Schaljo, Barbara, Vogl, Claus, Gattermeier, Irene, Kolbe, Thomas, Müller, Mathias, Blackshear, Perry J., Kovarik, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963709/
https://ncbi.nlm.nih.gov/pubmed/16514065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-3058
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