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Tristetraprolin limits inflammatory cytokine production in tumor-associated macrophages in an mRNA decay independent manner
Tristetraprolin (TTP) is an inducible zinc finger AU-rich RNA binding protein essential for enforcing degradation of mRNAs encoding inflammatory chemokines and cytokines. Most studies on TTP center on the connection between mRNA half-life and inflammatory output, because loss of TTP amplifies inflam...
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| Publicado no: | Cancer Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526390/ https://ncbi.nlm.nih.gov/pubmed/26183929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0205 |
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