Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation

For a successful yet controlled immune response, cells need to specifically destabilize inflammatory mRNAs but prevent premature removal of those still used. The regulatory circuits controlling quality and timing in the global inflammatory mRNA decay are not understood. Here, we show that the mRNA-d...

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Detalhes bibliográficos
Main Authors: Kratochvill, Franz, Machacek, Christian, Vogl, Claus, Ebner, Florian, Sedlyarov, Vitaly, Gruber, Andreas R, Hartweger, Harald, Vielnascher, Raimund, Karaghiosoff, Marina, Rülicke, Thomas, Müller, Mathias, Hofacker, Ivo, Lang, Roland, Kovarik, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737733/
https://ncbi.nlm.nih.gov/pubmed/22186734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.93
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