Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

Pancreatic islet amyloid deposits are a characteristic pathologic feature of non-insulin-dependent diabetes mellitus and contain islet amyloid polypeptide (IAPP; amylin). We used transgenic mice that express human IAPP in pancreatic beta cells to explore the potential role of islet amyloid in the pa...

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Auteurs principaux: Verchere, C B, D'Alessio, D A, Palmiter, R D, Weir, G C, Bonner-Weir, S, Baskin, D G, Kahn, S E
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC39637/
https://ncbi.nlm.nih.gov/pubmed/8622964
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