Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

Pancreatic islet amyloid deposits are a characteristic pathologic feature of non-insulin-dependent diabetes mellitus and contain islet amyloid polypeptide (IAPP; amylin). We used transgenic mice that express human IAPP in pancreatic beta cells to explore the potential role of islet amyloid in the pa...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Verchere, C B, D'Alessio, D A, Palmiter, R D, Weir, G C, Bonner-Weir, S, Baskin, D G, Kahn, S E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622964/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3492
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