eGFP Expression under UCHL1 Promoter Genetically Labels Corticospinal Motor Neurons and a Subpopulation of Degeneration-Resistant Spinal Motor Neurons in an ALS Mouse Model

Understanding mechanisms that lead to selective motor neuron degeneration requires visualization and cellular identification of vulnerable neurons. Here we report generation and characterization of UCHL1-eGFP and hSOD1(G93A)-UeGFP mice, novel reporter lines for cortical and spinal motor neurons. Cor...

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Main Authors: Yasvoina, Marina V., Genç, Barış, Jara, Javier H., Sheets, Patrick L., Quinlan, Katharina A., Milosevic, Ana, Shepherd, Gordon M.G., Heckman, C. J., Özdinler, P. Hande
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963467/
https://ncbi.nlm.nih.gov/pubmed/23637180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2787-12.2013
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