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eGFP Expression under UCHL1 Promoter Genetically Labels Corticospinal Motor Neurons and a Subpopulation of Degeneration-Resistant Spinal Motor Neurons in an ALS Mouse Model

Understanding mechanisms that lead to selective motor neuron degeneration requires visualization and cellular identification of vulnerable neurons. Here we report generation and characterization of UCHL1-eGFP and hSOD1(G93A)-UeGFP mice, novel reporter lines for cortical and spinal motor neurons. Cor...

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Main Authors: Yasvoina, Marina V., Genç, Barış, Jara, Javier H., Sheets, Patrick L., Quinlan, Katharina A., Milosevic, Ana, Shepherd, Gordon M.G., Heckman, C. J., Özdinler, P. Hande
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963467/
https://ncbi.nlm.nih.gov/pubmed/23637180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2787-12.2013
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