Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function

Corticospinal motor neurons (CSMN) receive, integrate, and relay cerebral cortex's input toward spinal targets to initiate and modulate voluntary movement. CSMN degeneration is central for numerous motor neuron disorders and neurodegenerative diseases. Previously, 5 patients with mutations in t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cereb Cortex
Hlavní autoři: Jara, Javier H., Genç, Barış, Cox, Gregory A., Bohn, Martha C., Roos, Raymond P., Macklis, Jeffrey D., Ulupınar, Emel, Özdinler, P. Hande
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626833/
https://ncbi.nlm.nih.gov/pubmed/25596590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhu318
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky