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Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

African trypanosomes are lethal human and animal parasites that use antigenic variation for evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate approximately one third of their nuclear genome, including many minichromosomes, and possibly all sub-telomeres, to...

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Bibliografische gegevens
Hoofdauteurs: Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963442/
https://ncbi.nlm.nih.gov/pubmed/24047558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12215
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