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Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

African trypanosomes are lethal human and animal parasites that use antigenic variation for evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate approximately one third of their nuclear genome, including many minichromosomes, and possibly all sub-telomeres, to...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark C, Horn, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963442/
https://ncbi.nlm.nih.gov/pubmed/24047558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12215
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