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Probing the chemistry of thioredoxin catalysis with force
Thioredoxins are enzymes that catalyse disulphide bond reduction in all living organisms(1). Although catalysis is thought to proceed through a substitution nucleophilic bimolecular (S(N)2) reaction(1,2), the role of the enzyme in modulating this chemical reaction is unknown. Here, using single-mole...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963401/ https://ncbi.nlm.nih.gov/pubmed/17972886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06231 |
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