Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)

Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that have the unique function of terminating cyclic nucleotide signaling by catalyzing the hydrolysis of cAMP and GMP. They are critical regulators of the intracellular concentrations of cAMP and cGMP as well as of their signaling pathways and...

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Autori principali: Azevedo, Monalisa F., Faucz, Fabio R., Bimpaki, Eirini, Horvath, Anelia, Levy, Isaac, de Alexandre, Rodrigo B., Ahmad, Faiyaz, Manganiello, Vincent, Stratakis, Constantine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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Reviews
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963262/
https://ncbi.nlm.nih.gov/pubmed/24311737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2013-1053
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