Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumors

BACKGROUND: Genetic aberrations in various components of cAMP signalling pathway predispose to endocrine tumors. Growing evidence has shown that mutations in the phosphodiesterases (PDEs) are involved in the predisposition to adrenocortical neoplastic conditions. OBJECTIVE: Screen for genetic variat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Rothenbuhler, Anya, Horvath, Anelia, Libé, Rossella, Faucz, Fabio Rueda, Fratticci, Amato, Sanson, Marie Laure Raffin, Vezzosi, Delphine, Azevedo, Monalisa, Levi, Isaak, Almeida, Madson Q, Lodish, Maya, Nesterova, Maria, Bertherat, Jérôme, Stratakis, Constantine A
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360985/
https://ncbi.nlm.nih.gov/pubmed/22335482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2012.04366.x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars