Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumors

BACKGROUND: Genetic aberrations in various components of cAMP signalling pathway predispose to endocrine tumors. Growing evidence has shown that mutations in the phosphodiesterases (PDEs) are involved in the predisposition to adrenocortical neoplastic conditions. OBJECTIVE: Screen for genetic variat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rothenbuhler, Anya, Horvath, Anelia, Libé, Rossella, Faucz, Fabio Rueda, Fratticci, Amato, Sanson, Marie Laure Raffin, Vezzosi, Delphine, Azevedo, Monalisa, Levi, Isaak, Almeida, Madson Q, Lodish, Maya, Nesterova, Maria, Bertherat, Jérôme, Stratakis, Constantine A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360985/
https://ncbi.nlm.nih.gov/pubmed/22335482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2012.04366.x
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk