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Enzymology of RNA cap synthesis
The 5′ guanine-N7 methyl cap is unique to cellular and viral messenger RNA (mRNA) and is the first co-transcriptional modification of mRNA. The mRNA cap plays a pivotal role in mRNA biogenesis and stability, and is essential for efficient splicing, mRNA export, and translation. Capping occurs by a s...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962952/ https://ncbi.nlm.nih.gov/pubmed/21956912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.19 |
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