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Enzymology of RNA cap synthesis

The 5′ guanine-N7 methyl cap is unique to cellular and viral messenger RNA (mRNA) and is the first co-transcriptional modification of mRNA. The mRNA cap plays a pivotal role in mRNA biogenesis and stability, and is essential for efficient splicing, mRNA export, and translation. Capping occurs by a s...

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Detalhes bibliográficos
Main Authors: Ghosh, Agnidipta, Lima, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962952/
https://ncbi.nlm.nih.gov/pubmed/21956912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.19
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