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Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo
Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediate...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962508/ https://ncbi.nlm.nih.gov/pubmed/24701377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27614 |
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