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Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediate...

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Detalhes bibliográficos
Main Authors: Sandin, Linda C, Eriksson, Fredrik, Ellmark, Peter, Loskog, Angelica SI, Tötterman, Thomas H, Mangsbo, Sara M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962508/
https://ncbi.nlm.nih.gov/pubmed/24701377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27614
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