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TDP-43 in ALS: Stay on target… Almost there

ALS is associated with RNA processing impairments involving the RNA-binding protein TDP-43. Pioneering a novel RNA beacon to illuminate RNA trafficking in neurons, Alami et al. discover a novel cytoplasmic function for TDP-43, suggesting a new disease mechanism.

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Detalhes bibliográficos
Main Authors: Jovičić, Ana, Gitler, Aaron D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962496/
https://ncbi.nlm.nih.gov/pubmed/24507183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.034
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