In Vivo Determination of Direct Targets of the Nonsense-Mediated Decay Pathway in Drosophila

Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a mRNA degradation pathway that regulates a significant portion of the transcriptome. The expression levels of numerous genes are known to be altered in NMD mutants, but it is not known which of these transcripts is a direct pathway target. Here,...

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Bibliographic Details
Main Authors: Chapin, Alex, Hu, Hao, Rynearson, Shawn G., Hollien, Julie, Yandell, Mark, Metzstein, Mark M.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2014
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962487/
https://ncbi.nlm.nih.gov/pubmed/24429422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.009357
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