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Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6
The nonsense-mediated mRNA decay (NMD) pathway is best known for targeting mutant mRNAs containing premature termination codons for rapid degradation, but it is also required for regulation of many endogenous transcripts. Components of the NMD pathway were originally identified by forward genetic sc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404369/ https://ncbi.nlm.nih.gov/pubmed/22740637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032821.112 |
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