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Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6

The nonsense-mediated mRNA decay (NMD) pathway is best known for targeting mutant mRNAs containing premature termination codons for rapid degradation, but it is also required for regulation of many endogenous transcripts. Components of the NMD pathway were originally identified by forward genetic sc...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Frizzell, Kimberly A., Rynearson, Shawn G., Metzstein, Mark M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404369/
https://ncbi.nlm.nih.gov/pubmed/22740637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032821.112
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