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Nonsense-mediated mRNA decay in Drosophila:at the intersection of the yeast and mammalian pathways
The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature stop codons (PTCs). In Caenorhabditis elegans, seven genes (smg1–7) playing an essential role in NMD have been identified. Only SMG2–4 (known as UPF1–3) have orthologs in Saccharomyces cerevis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169044/ https://ncbi.nlm.nih.gov/pubmed/12881430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg371 |
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