Nonsense-mediated mRNA decay in Drosophila:at the intersection of the yeast and mammalian pathways

The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature stop codons (PTCs). In Caenorhabditis elegans, seven genes (smg1–7) playing an essential role in NMD have been identified. Only SMG2–4 (known as UPF1–3) have orthologs in Saccharomyces cerevis...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Gatfield, David, Unterholzner, Leonie, Ciccarelli, Francesca D., Bork, Peer, Izaurralde, Elisa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12881430/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg371
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