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Nonsense-mediated mRNA decay in Drosophila:at the intersection of the yeast and mammalian pathways

The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature stop codons (PTCs). In Caenorhabditis elegans, seven genes (smg1–7) playing an essential role in NMD have been identified. Only SMG2–4 (known as UPF1–3) have orthologs in Saccharomyces cerevis...

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Bibliografische gegevens
Hoofdauteurs: Gatfield, David, Unterholzner, Leonie, Ciccarelli, Francesca D., Bork, Peer, Izaurralde, Elisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC169044/
https://ncbi.nlm.nih.gov/pubmed/12881430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg371
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