LINE-1 DNA Methylation, Smoking and Risk of Parkinson’s Disease

Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation and survival o...

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Bibliographic Details
Main Authors: Nielsen, Susan Searles, Checkoway, Harvey, Butler, Rondi A., Nelson, Heather H., Farin, Federico M., Longstreth, W.T., Franklin, Gary M., Swanson, Phillip D., Kelsey, Karl T.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962286/
https://ncbi.nlm.nih.gov/pubmed/23938260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-012129
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