LINE-1 DNA Methylation, Smoking and Risk of Parkinson’s Disease

Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation and survival o...

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Main Authors: Nielsen, Susan Searles, Checkoway, Harvey, Butler, Rondi A., Nelson, Heather H., Farin, Federico M., Longstreth, W.T., Franklin, Gary M., Swanson, Phillip D., Kelsey, Karl T.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962286/
https://ncbi.nlm.nih.gov/pubmed/23938260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-012129
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