LINE-1 DNA Methylation, Smoking and Risk of Parkinson’s Disease

Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation and survival o...

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Detalhes bibliográficos
Main Authors: Nielsen, Susan Searles, Checkoway, Harvey, Butler, Rondi A., Nelson, Heather H., Farin, Federico M., Longstreth, W.T., Franklin, Gary M., Swanson, Phillip D., Kelsey, Karl T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962286/
https://ncbi.nlm.nih.gov/pubmed/23938260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-012129
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