LINE-1 DNA Methylation, Smoking and Risk of Parkinson’s Disease

Long interspersed nucleotide element-1 (LINE-1) retrotransposons are located throughout the human genome. Those retaining an intact 5′ promoter can copy and insert themselves into the DNA of neural progenitor cells that express tyrosine hydroxylase, which may influence differentiation and survival o...

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Détails bibliographiques
Auteurs principaux: Nielsen, Susan Searles, Checkoway, Harvey, Butler, Rondi A., Nelson, Heather H., Farin, Federico M., Longstreth, W.T., Franklin, Gary M., Swanson, Phillip D., Kelsey, Karl T.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962286/
https://ncbi.nlm.nih.gov/pubmed/23938260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-012129
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