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Structure and Permeability of Ion-channels by Integrated AFM and Waveguide TIRF Microscopy

Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate. Solid substrate prevents molecular transport through ion channels thus hindering any direct...

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Detalhes bibliográficos
Main Authors: Ramachandran, Srinivasan, Arce, Fernando Teran, Patel, Nirav R., Quist, Arjan P., Cohen, Daniel A., Lal, Ratnesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961736/
https://ncbi.nlm.nih.gov/pubmed/24651823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04424
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